Baxter Box Equipment Loaner Program

We have the lab equipment you need to bring the life sciences to your classroom. Teachers who are trained in our professional development workshops are given free access to our Baxter Box materials and equipment loaner program.

Questions? Contact bcse@northwestern.edu

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Available Activities

Antibiotic Sensitivity

Antibiotic Sensitivity

Students study the effect of 6 different antibiotics on a Gram-positive bacterium and a Gram-negative bacterium.

More info on the kit can be found here

Bradford Activity

Bradford Activity

The Bradford Assay is a quick and easy way to measure total protein concentration in a sample. The assay can be used to measure actual protein concentrations such as the protein quantities in food.
Cancer Gene Detection

Cancer Gene Detection

Immortality through uncontrolled cell division is a characteristic of cancer cells. The p53 gene is a tumor suppressor gene which prevents this. Mutations in this gene are present in more than 50% of cancers. Testing people for mutations in their p53 gene can indicate an increased risk in developing cancer. These tests raise intriguing ethical questions for both the individual tested and the family of an individual who chooses to be tested. In this experiment, students determine a pedigree for a family suspected to be carriers of mutations in their p53 genes. A DNA test indicates their likelihood of developing cancer.
Candy Dye Gel Electrophoresis

Candy Dye Gel Electrophoresis

Introduce your students to the basic principles and operation of gel electrophoresis with this quick and easy experiment using colorful candy dyes. Students learn how biological molecules are separated during electrophoresis by comparing the charge and size of dyes they extract themselves. Students observe the direction and measure the rate of migration of the dyes.
Comparative Proteomics

Comparative Proteomics

Grind up fish from the supermarket and analyze their proteins with SDS-PAGE (protein gel electrophoresis). You’ll find evidence for evolution at the protein level.
Crime Scene Investigator

Crime Scene Investigator

This activity serves as an introduction to PCR for students by allowing them to simulate DNA profiling as it is commonly used in forensic laboratories. The laboratory is performed without the need for complex genomic DNA extraction steps.
DNA Damage & Repair

DNA Damage & Repair

UV light really does damage DNA! Design your own experiment to find out more about how UV light damages DNA and visualize the damage with Gel Electrophoresis.
ELISA Immuno Explorer

ELISA Immuno Explorer

Students use a technique referred to as enzyme-linked immunosorbent assay (ELISA) to detect the presence of an antibody or an antigen in a sample. The protocol uses two antibodies, one of which is specific to the antigen and another that is coupled to an enzyme. This second antibody gives the assay its enzyme-linked name and causes a chromogenic substrate to produce color wherever it is bound.
Genotype to Phenotype - PTC Taster Lab

Genotype to Phenotype - PTC Taster Lab

Students examine how small genetic variations called single nucleotide polymorphisms (SNPs) can change our ability to perceive the world around us. The human sense of taste is composed of an intricate neurophysiological network, but as we’ll see in this lab, it only takes a few small changes in our DNA to change the way we taste.
GMO Investigator

GMO Investigator

Students engage in a complete investigation in which they gather sample food items from the grocery store, extract DNA from the samples, amplify the DNA using polymerase chain reaction (PCR), and use agarose gel electrophoresis to identify the presence or absence of amplified GMO sequences.
Green Fluorescent Protein Chromatography

Green Fluorescent Protein Chromatography

Purify Green Fluorescent Protein (GFP) from jellyfish with the same techniques used to make many pharmaceuticals. An extension of pGLO Bacterial Transformation.
Mini-toobers

Mini-toobers

Model protein folding and build your own protein!
pGLO SDS-PAGE Extension

pGLO SDS-PAGE Extension

In this laboratory activity, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is used to separate the entire repertoire of proteins expressed in the transformed E. coli from the pGLO transformation activity, including the foreign GFP responsible for transferring the fluorescence trait.
pGLO Transformation

pGLO Transformation

Students perform a procedure known as genetic transformation to transfer the Green Flourescent Protein DNA sequence from a stock of lyophilized plasmid into E. coli. The pGLO DNA sequence is placed under the control of an inducible promoter, and when plated on agar plates containing the inducer (in this lab,the sugar arabinose), the gene is expressed and the colonies of E. coli fluoresce bright green.
Photosynthesis and Cellular Respiration

Photosynthesis and Cellular Respiration

Teach both photosynthesis and cellular respiration simultaneously in a single lab. The Photosynthesis and Cellular Respiration Kit for AP Biology is a fun, easy to use, and more reliable alternative to the leaf disk and microrespirometer labs. Use the novel algae beads in this kit to help you dispel the common student misconception that plants do only photosynthesis, and only animals do cellular respiration.

Students will explore both photosynthesis and cellular respiration in a single organism (an alga) using a simple colorimetric assay to yield qualitative and/or quantitative results. The included student and teacher manuals will guide you and your students through a series of structured, guided, and open inquiry investigations.

Pipette by Numbers

Pipette by Numbers

Practice pipetting in a fun and artistic way!
Purification of Green and Blue Fluorescent Proteins

Purification of Green and Blue Fluorescent Proteins

In this experiment, bacterial extracts containing gfp or bfp will be fractionated by chro-matography using a molecular sieve matrix.  Factors that affect the separation include size, shape and associated non-protein biologicals such as carbohydrate residues.  The fl uorescent proteins will be detected on the column and subsequently in the test tubes by examination under long U.V. light.

Restriction Digest and Analysis of Lambda DNA

Restriction Digest and Analysis of Lambda DNA

Students use three different restriction enzymes to digest genomic DNA from lambda bacteriophage. By visualizing the effects of three different enzymes on identical samples of double-stranded DNA, students learn that different restriction enzymes recognize and cut different DNA sequences.
Simulated Blood Typing "Whodunit"

Simulated Blood Typing "Whodunit"

Students attempt to solve a crime by matching the blood type of samples found at the "scene" with those of several suspects. After extracting samples from crime scene fabric stained with simulated blood, students can analyze them under the microscope, and perform blood type analysis to match the blood type with one of four suspects to help identify the culprit.
Space Food Safety Lab

Space Food Safety Lab

In this lab, you will help the International Space Agency control an outbreak of pathogenic bacteria in space food bound for Mars! Learn how to use PCR, restriction analysis, and DNA gel electrophoresis to characterize bacterial strains and protect the health of astronauts.

Available Lab Equipment/Kits

Centrifuge

Centrifuge

A centrifuge spins materials at high speeds to push heavier materials to the bottom using centrifugal force.

This kit contains the following components:

  • 1 Centrifuge
Dry Bath

Dry Bath

A dry bath is used to incubate samples at a constant temperature over a period of time.

This kit contains the following components:

  • 1 Dry Bath
Fixed Volume Pipette Kit

Fixed Volume Pipette Kit

Fixed volume pipettes are used to move small volumes of liquid.

This kit contains the following components:

  • 25 five-microliter pipettes
  • 25 ten-microliter pipettes
  • Disposable pipette tips
Horizontal Gel Box Kit

Horizontal Gel Box Kit

Gel electrophoresis is used for DNA analysis.

This kit contains the following components:

  • 8 Gel Boxes and supplies
  • 2 Centrifuges
  • 1 Dry Bath
  • 2 Transilluminators
Incubator

Incubator

Incubators provide a controlled environment in which to grow microorganisms.

This kit contains the following components:

  • 1 Incubator
  • Optional: Bacterial Cultures
Mini-Toober Kit

Mini-Toober Kit

Mini-Toobers are used to model proteins and protein folding.

This kit contains the following components:

  • 30 Mini-Toobers
  • Multi-Colored Thumb Tacks
Pill Box Gel Electrophoresis Kit

Pill Box Gel Electrophoresis Kit

DIY Gel electrophoresis can be used for DNA analysis.

This kit contains the following components:

  • 16 Pill Boxes
  • 48 9-volt Batteries
  • 32 Connector Cables
Pipette Kit

Pipette Kit

Pipettes are used to move small volumes of liquid.

This kit contains the following components:

  • 8 p20 Pipettes
  • 8 p200 Pipettes
  • 8 p1000 Pipettes
  • Disposable Pipette Tips
SDS-PAGE Kit for Protein Analysis

SDS-PAGE Kit for Protein Analysis

SDS-PAGE is used for protein analysis.

This kit contains the following components:

  • 4 Gel Boxes and supplies
  • 2 Centrifuges
  • 1 Dry Bath
  • 2 Transilluminators
Spectrophotometer

Spectrophotometer

Spectrophotometers are used to measure the intensity of light as it is transmitted or emitted by particular substances.

This kit contains the following components:

  • 1 Spectrophotometer
  • Cuvettes
Stir Plate

Stir Plate

A stir plate is a laboratory device that uses a rotating magnetic field to cause a stir bar immersed in a liquid to spin very quickly, stirring it.

This kit contains the following components:

  • 1 Stir Plate
  • Stir Bars
Thermocycler

Thermocycler

Thermocyclers are used to amplify DNA and RNA samples by the Polymerase Chain Reaction (PCR).

This kit contains the following components:

  • 1 Thermocycler
UV Transilluminator

UV Transilluminator

UV Transilluminators are used to visualize DNA gels.

This kit contains the following components:

  • 1 UV Transilluminator
Vortexer

Vortexer

A vortex mixer or vortexer is used to mix small containers of liquid.

This kit contains the following components:

  • 1 Vortexer
Water Bath

Water Bath

Water baths are used to incubate samples in water at a constant temperature over a long period of time.

This kit contains the following components:

  • 1 Water Bath